Contract projects for industries and contract research for Major Corporation, for their standardization program involving microbial metabolites, herbal products and new drug discovery.
Research in synthetic chemistry and Biotechnology
Collaborative research and product development of API and its intermediates.
Isolation of secondary metabolites from Fungus, Bacteria through optimized fermentation conditions.
Studies on Bio pesticides –Shelf life studies, Stability testing, Compatibility testing, residual analysis. Isolation of Fungal, Bacterial Endophytes from Medicinal Plants, trees, Algae& Sea weeds etc.
Extraction & Analysis of Pigments–Melanin, Carotenoids Xanthophylls
Synthesis of Nanoparticles using fungal mat.
Synthesis of Active pharmaceutical ingredients (API) by novel routes.
Synthesis of drug Impurities in Active pharmaceutical ingredients.
Synthesis of Flavanoides and other Antioxidants.
Synthesis of Chiral molecules and its Asymmetric synthesis
Expertise in conducting reactions with sensitive organic compounds
The key sectors supported include agricultural, herbal, food, chemical and pharmaceutical. Our analytical team has a proven expertise in performing decisive tests and interpreting results of qualitative, quantitative and structural analysis. We also offer well structured courses for analytical procedures for students and knowledge transfer on various experimental techniques to corporate staff.
Biotechnology services include microbiological analysis, production of microbial metabolites through optimized fermentation bio-activity studies, sensitivity studies, anti-oxidant assay for plant and food components, production of secondary metabolites, microbiological enzyme production and its assay, biotransformation, protein studies, microbiological pathogen studies.
The chemical services delivered include structural determination of molecules, Herbal extraction and identification of phyto-chemicals, new drug discovery, Custom synthesis (small and large scale), Impurity profile of compounds, Catalogue synthesis
Process for preparation of Tamsulosin and its derivatives, Hwu JIH Ru, Magendran Balachari et al, EP 1734036A1
Process for preparation of Tamsulosin and its Aralkylamine derivatives , Hwu JIH Ru, Shwu Chen Tsay, Magendran Balachari, et al , US 20070015939A1.
Synthesis of Novel bioactive Bi and Tridentate Chiral molecules from Valine and Phenyl alanine, Magendran Balachari, Menaga and Narasimhan.S filed in Indian patent , IP; July 2012
Synthesis of Biological active compounds of some Nucleic acids (Communicated - Journal of medicinal chemistry).
Synthesis, Characterization and Molecular docking of Bi and Tridentate Chiral molecules for HIV-Native protease. Magendran Balachari, Narasimhan. S, Journal of Chemical and Pharmaceutical research, 2012, 4(8):4001 -4006.
Synthesis of a chiral Schiff base derived metal complexes and its antibacterial studies. Magendran Balachari, Menaga and Narasimhan.S (Journal of Chemical and Pharmaceutical research, 2012, 4(11):4731- 4736.
a) Development of product/process and do technology transfer in
Chemistry (Synthesis of API, Intermediate, Impurities and fine chemicals )
Analytical ( analysis and method validation)
b) Interested in Isolation , Purification, screening and determining biological activity of natural products
c) Drug discovery, Custom research and New chemical entity .